Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
Taci_0750PFAM: CBS domain containing protein; Polynucleotide adenylyltransferase region; phosphoesterase RecJ domain protein; SMART: CBS domain containing protein; KEGG: gsu:GSU1581 polyA polymerase family protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (867 aa)    
Predicted Functional Partners:
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
   0.919
Taci_1593
PFAM: dihydrodipicolinate reductase; KEGG: bcr:BCAH187_A1699 dihydrodipicolinate reductase; Belongs to the DapB family.
  
  
 0.885
Taci_0748
PFAM: UvrD/REP helicase; KEGG: bha:BH0648 ATP-dependent DNA helicase.
  
  
 0.865
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
  
 0.849
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.804
Taci_1010
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
    0.788
Taci_0751
PFAM: peptidase M50; KEGG: dps:DP0062 hypothetical protein.
       0.784
Taci_1079
DNA polymerase I; KEGG: bcy:Bcer98_3272 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; SMART: 5'-3' exonuclease; DNA-directed DNA polymerase; Helix-hairpin-helix domain protein class 2.
  
  
 0.781
rny
RNA binding metal dependent phosphohydrolase; Endoribonuclease that initiates mRNA decay.
  
  
 0.770
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
 
 0.765
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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