STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Taci_0772PFAM: phosphoribosyltransferase; KEGG: bsu:BSU00470 purine operon repressor. (264 aa)    
Predicted Functional Partners:
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
 
 0.909
ispE
4-(cytidine 5'-diphospho)-2-C-methyl-D- erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
  
    0.831
Taci_0770
KEGG: bcy:Bcer98_0038 hypothetical protein.
 
     0.744
Taci_0773
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dps:DP1865 ferredoxin.
       0.630
Taci_0661
KEGG: ank:AnaeK_0247 phosphoribosyltransferase.
   
    0.612
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
  
 0.612
purH
KEGG: scl:sce3150 IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; SMART: AICARFT/IMPCHase bienzyme formylation region.
  
 
 0.609
Taci_1638
PFAM: Prephenate dehydrogenase; KEGG: mca:MCA1416 prephenate dehydrogenase.
  
  
 0.600
Taci_1102
Transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; KEGG: bcb:BCB4264_A3953 hypothetical protein.
  
    0.562
codY
GTP-sensing pleiotropic transcriptional repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
  
  
 0.555
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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