STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
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[Homology]
Score
Taci_0788Primosomal protein N' (replication factor Y) - superfamily II helicase-like protein; KEGG: mpt:Mpe_A0133 replication restart DNA helicase PriA. (602 aa)    
Predicted Functional Partners:
Taci_0787
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
  
    0.903
Taci_0651
TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: mxa:MXAN_1071 single-strand binding protein.
 
 
 
 0.883
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
    0.830
Taci_0783
PFAM: domain of unknown function DUF1732; YicC domain protein; KEGG: gme:Gmet_2328 hypothetical protein.
  
    0.824
Taci_0784
PFAM: protein of unknown function DUF370; KEGG: dds:Ddes_1405 protein of unknown function DUF370; Belongs to the RemA family.
       0.819
Taci_0786
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
       0.813
der
Small GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
       0.721
Taci_0279
PFAM: formyl transferase domain protein; KEGG: gme:Gmet_0884 hypothetical protein.
  
    0.710
fmt
Formyl transferase domain protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
    0.710
cmk
TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: gsu:GSU2605 cytidylate kinase.
  
    0.691
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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