STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
nfoApurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (277 aa)    
Predicted Functional Partners:
Taci_0833
TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; PEP-utilising protein mobile region; HpcH/HpaI aldolase; Pyruvate kinase alpha/beta; KEGG: bha:BH3163 pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.862
Taci_0065
TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: sfu:Sfum_2331 exodeoxyribonuclease III Xth.
    
 
 0.850
Taci_0834
PFAM: NUDIX hydrolase; KEGG: rsh:Rsph17029_2867 NUDIX hydrolase.
     
 0.826
Taci_0980
DNA-(apurinic or apyrimidinic site) lyase; KEGG: similar to endonuclease III; K10773 endonuclease III; PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein; iron-sulfur cluster loop.
  
 
 0.781
Taci_1578
KEGG: sfu:Sfum_0347 hypothetical protein.
  
 
 0.781
Taci_0832
PFAM: tryptophan RNA-binding attenuator protein; KEGG: bsu:BSU22770 transcription attenuation protein MtrB.
       0.762
Taci_1706
TIGRFAM: hydrolase, HAD-superfamily, subfamily IIIA; histidinol-phosphate phosphatase family protein; KEGG: msl:Msil_0986 histidinol-phosphate phosphatase family protein.
   
 
 0.746
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
     0.740
Taci_0831
KEGG: sfu:Sfum_1225 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; SMART: phosphoesterase PHP domain protein.
     
 0.728
Taci_0836
PFAM: alanine racemase domain protein; KEGG: mlo:mlr5700 hypothetical protein.
       0.701
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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