Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Taci_0920TIGRFAM: SpoIID/LytB domain protein; PFAM: Stage II sporulation D domain protein; KEGG: gur:Gura_1714 SpoIID/LytB domain-containing protein. (437 aa)    
Predicted Functional Partners:
queA
S-adenosylmethionine/tRNA-ribosyltransferase-iso merase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
       0.820
Taci_0918
PFAM: AMMECR1 domain protein; Extradiol ring- cleavage dioxygenase class III protein subunit B; KEGG: afr:AFE_0573 conserved hypothetical protein TIGR00296.
       0.722
Taci_0484
PFAM: polysaccharide pyruvyl transferase; KEGG: bat:BAS0840 CsaB protein.
  
     0.683
Taci_0489
PFAM: Peptidase M23; KEGG: gsu:GSU1773 M23/M37 peptidase domain- containing protein.
  
     0.676
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
     
 0.643
ruvA
RuvA domain protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
       0.635
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
       0.634
Taci_0925
PFAM: protein of unknown function DUF28; KEGG: dal:Dalk_2958 protein of unknown function DUF28.
       0.634
Taci_0917
PFAM: Radical SAM domain protein; KEGG: nis:NIS_1749 [pyruvate formate-lyase]- activating enzyme.
       0.620
Taci_0921
KEGG: aba:Acid345_4440 hypothetical protein.
       0.590
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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