Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (331 aa)    
Predicted Functional Partners:
Taci_1239
KEGG: mxa:MXAN_3466 aspartate kinase, monofunctional class; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family.
 
 
 0.997
Taci_0506
PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: rlt:Rleg2_5063 homoserine dehydrogenase.
 
 0.985
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
  
 0.923
Taci_1241
TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bha:BH3421 threonine synthase.
  
 
 0.901
Taci_0449
PFAM: aspartate/glutamate/uridylate kinase; KEGG: predicted protein; K00930 acetylglutamate kinase.
  
 
 0.621
Taci_1236
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: gsu:GSU1888 ABC transporter, ATP-binding protein.
       0.594
Taci_1237
PFAM: OstA family protein; KEGG: hne:HNE_0204 OstA family protein.
       0.594
Taci_0833
TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; PEP-utilising protein mobile region; HpcH/HpaI aldolase; Pyruvate kinase alpha/beta; KEGG: bha:BH3163 pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.585
aroK
Shikimate kinase., 3-dehydroquinate synthase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
  
  
 0.584
Taci_0141
PFAM: homocysteine S-methyltransferase; cobalamin B12-binding domain protein; Methionine synthase B12- binding module cap domain protein; dihydropteroate synthase DHPS; KEGG: gsu:GSU2921 5-methyltetrahydrofolate- homocysteine methyltransferase, truncation.
  
  
 0.583
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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