Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Taci_1272PFAM: glutamine synthetase catalytic region; KEGG: dde:Dde_0102 glutamine synthetase, type III. (699 aa)    
Predicted Functional Partners:
Taci_1547
Glutamate--ammonia ligase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: acp:A2cp1_4408 glutamine synthetase, type I.
    
 0.924
Taci_0188
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: mms:mma_0278 glutamate dehydrogenase (NAD(P)+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.911
Taci_0319
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: ppd:Ppro_1713 Glu/Leu/Phe/Val dehydrogenase, C terminal; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.911
Taci_1111
TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sat:SYN_00606 glutamate synthase (NADPH).
    
 0.910
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
    
  0.906
Taci_1504
TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; RimK domain protein ATP-grasp; phosphoribosylglycinamide synthetase; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; protein of unknown function DUF201; KEGG: bha:BH2536 carbamoyl phosphate synthase large subunit; Belongs to the CarB family.
  
 
  0.901
Taci_0269
Carbamate kinase; KEGG: bcb:BCB4264_A0423 carbamate kinase; TIGRFAM: carbamate kinase; PFAM: aspartate/glutamate/uridylate kinase; Belongs to the carbamate kinase family.
     
  0.900
Taci_0315
Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: mxa:MXAN_0212 aminotransferase, class I and II family protein.
     
  0.900
Taci_0592
Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: bpt:Bpet4860 putative aminotransferase.
     
  0.900
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
     
  0.900
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
Server load: low (36%) [HD]