STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (509 aa)    
Predicted Functional Partners:
Taci_1557
PFAM: major intrinsic protein; KEGG: azc:AZC_2711 glycerol uptake facilitator protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.967
plsY
Protein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
    
 0.928
Taci_0715
Protease Do; KEGG: gbm:Gbem_3394 protease Do; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; Peptidase S7 flavivirus helicase (NS3); PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein.
   
 0.915
Taci_1411
PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: oca:OCAR_6572 protease Do subfamily.
   
 0.915
Taci_1459
TIGRFAM: PTS system, glucose-specific IIBC subunit; PTS system, glucose subfamily, IIA subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system EIIC; sugar- specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; KEGG: bha:BH0844 PTS system, glucose-specific enzyme II, A component.
  
 
 0.819
Taci_0069
PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: bsu:BSU09620 hypothetical protein.
 
  
 0.778
Taci_1285
PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; KEGG: sus:Acid_0085 ABC transporter related.
   
 0.773
Taci_0576
PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: pmy:Pmen_0801 ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
    
 0.754
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
 
 0.749
Taci_1496
KEGG: dno:DNO_0181 hypothetical protein.
   
  0.744
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.