Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Taci_1681KEGG: bsu:BSU35790 mannose-6-phosphate isomerase; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I. (312 aa)    
Predicted Functional Partners:
Taci_0016
KEGG: dol:Dole_2031 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Nucleotidyl transferase; Cupin 2 conserved barrel domain protein; mannose-6-phosphate isomerase type II.
 
 0.995
Taci_1684
TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose- specific IIB subunit; phosphotransferase system EIIC; KEGG: bcy:Bcer98_1170 PTS system, fructose subfamily, IIC subunit.
  
 
 0.987
Taci_0794
PFAM: phosphoglucose isomerase (PGI); KEGG: afw:Anae109_2086 glucose-6-phosphate isomerase.
 
 
 0.958
Taci_0468
Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; KEGG: afw:Anae109_0166 phosphomannomutase.
 
 
 0.955
glmS
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.927
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
 
  
 0.919
pfp
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
 
  
 0.919
nagB
Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
     
 0.916
Taci_1013
Fructose-1,6-bisphosphatase, class II; KEGG: dvl:Dvul_1592 fructose 1,6-bisphosphatase II; TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein.
     
  0.900
Taci_0535
PFAM: ROK family protein; KEGG: gbm:Gbem_1326 ROK family protein.
 
  
 0.890
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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