STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (220 aa)    
Predicted Functional Partners:
Taci_1709
TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: gme:Gmet_2909 phosphomethylpyrimidine kinase.
 
 0.999
Taci_1710
Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ). Belongs to the Thz kinase family.
 
 0.999
Taci_1359
TIGRFAM: thiamine biosynthesis protein ThiC; PFAM: thiamine biosynthesis protein ThiC; KEGG: gme:Gmet_2910 thiamine biosynthesis protein ThiC.
  
 0.974
Taci_0198
KEGG: bce:BC2986 alkaline phosphatase; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; Belongs to the alkaline phosphatase family.
    
  0.900
Taci_0145
PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: sfu:Sfum_0842 thiamine biosynthesis protein ThiH.
  
  
 0.885
Taci_0802
TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: csa:Csal_3147 thiamine biosynthesis protein ThiS.
  
  
 0.880
Taci_1712
TIGRFAM: thiW protein; KEGG: bav:BAV1079 BioY-family membrane protein.
 
     0.869
Taci_1588
PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: ppd:Ppro_0890 UBA/ThiF-type NAD/FAD binding protein.
 
  
 0.828
Taci_1713
PFAM: Radical SAM domain protein; KEGG: glo:Glov_0108 radical SAM domain protein.
       0.661
Taci_0095
TIGRFAM: phosphate binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: sat:SYN_00056 ABC-type phosphate transport system, periplasmic component.
   
    0.596
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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