Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tter_0002TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein; KEGG: gme:Gmet_1987 biotin--acetyl-CoA-carboxylase ligase. (262 aa)    
Predicted Functional Partners:
Tter_1621
Propionyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: ade:Adeh_0250 carboxyl transferase.
 
 
 0.880
Tter_1643
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.870
Tter_1619
PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: rec:RHECIAT_CH0003763 probable biotin carboxylase protein.
  
 0.856
Tter_1164
PFAM: protein of unknown function DUF201; phosphoribosylglycinamide synthetase; KEGG: ade:Adeh_2440 biotin carboxylase-like.
  
 0.845
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
     
 0.795
Tter_0045
PFAM: peptidase M22 glycoprotease; KEGG: sfu:Sfum_1786 peptidase M22, glycoprotease.
  
    0.578
coaX
Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
 
    0.562
Tter_2620
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.548
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.539
Tter_0003
PFAM: GCN5-related N-acetyltransferase; KEGG: afr:AFE_2515 ribosomal-protein-alanine acetyltransferase.
  
    0.536
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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