Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (303 aa)    
Predicted Functional Partners:
Tter_0119
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
 
 0.998
Tter_0844
PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: xac:XAC1820 bifunctional aspartokinase I/homeserine dehydrogenase I.
 
 0.995
metXA
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
     
 0.914
Tter_2640
Phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; KEGG: lch:Lcho_1977 phosphoribosylformylglycinamidine cyclo-ligase.
 
    
 0.909
Tter_0433
PFAM: aminoglycoside phosphotransferase; KEGG: bcb:BCB4264_A2807 hypothetical protein.
     
  0.900
Tter_1187
PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: scl:sce8634 bifunctional homocysteine S- methyltransferase/5,10-methylenetetrahydrofolate reductase protein.
  
 
 0.900
Tter_1212
Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: sus:Acid_3250 cystathionine gamma-synthase.
  
 
 0.832
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.831
ilvE-2
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.831
Tter_1545
PFAM: aminotransferase class IV; KEGG: azc:AZC_1597 4-amino-4-deoxychorismate lyase.
  
 
 0.831
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.