STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tter_0228Threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: sfu:Sfum_0699 threonine aldolase. (353 aa)    
Predicted Functional Partners:
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 0.934
Tter_0227
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: gur:Gura_4035 threonine dehydratase.
  
 
 0.929
Tter_0119
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
 0.925
gcvPB
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
    
 0.925
gcvPA
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
    
 0.923
Tter_0163
Alanine--glyoxylate transaminase; PFAM: aminotransferase class V; KEGG: ade:Adeh_2994 alanine-glyoxylate aminotransferase.
    
 0.917
Tter_1850
TIGRFAM: GTP-binding protein YchF; PFAM: Protein of unknown function DUF933; KEGG: aba:Acid345_3198 translation-associated GTPase.
      0.824
Tter_0229
PFAM: NMT1/THI5 like domain protein; SMART: extracellular solute-binding protein family 3; KEGG: rpd:RPD_2108 extracellular solute-binding protein.
       0.528
Tter_0230
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sml:Smlt2573 putative ATP-binding ABC transporter protein.
       0.518
Tter_0231
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mlo:mlr7951 ABC transporter, permease.
       0.518
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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