Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fumCFumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (472 aa)    
Predicted Functional Partners:
Tter_0785
KEGG: sfu:Sfum_2104 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; succinate dehydrogenase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase.
 
 0.994
Tter_1189
PFAM: Citrate synthase; KEGG: bsu:BSU29140 methylcitrate synthase; Belongs to the citrate synthase family.
   
 0.981
Tter_0784
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: sfu:Sfum_2103 succinate dehydrogenase and fumarate reductase iron-sulfur protein.
  
 0.963
Tter_0787
TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: succinate dehydrogenase, cytochrome b subunit; K00241 succinate dehydrogenase cytochrome b-556 subunit.
   
 
 0.952
Tter_1224
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.944
Tter_0786
KEGG: wbm:Wbm0485 succinate dehydrogenase subunit D SdhD, hydrophobic membrane anchor protein.
   
 
 0.922
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
   
 0.840
argH
KEGG: fph:Fphi_0553 argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase.
   
 
 0.836
Tter_0256
PFAM: aminotransferase class I and II; KEGG: mgm:Mmc1_0698 L-aspartate aminotransferase.
    
 0.825
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
    
  0.806
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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