STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tter_0434PFAM: aminotransferase class I and II; KEGG: sus:Acid_3616 aminotransferase. (393 aa)    
Predicted Functional Partners:
Tter_1187
PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: scl:sce8634 bifunctional homocysteine S- methyltransferase/5,10-methylenetetrahydrofolate reductase protein.
  
 
 0.953
Tter_2737
Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: eba:ebA4598 cystathionine beta-lyase, putative, gene: MetC.
 
 
 0.930
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 0.922
metE
5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
   
 
 0.911
Tter_2133
PFAM: homocysteine S-methyltransferase; KEGG: hypothetical protein.
   
 
 0.907
Tter_2363
PFAM: GAF domain protein; SMART: GAF domain protein; KEGG: aba:Acid345_2653 putative GAF sensor protein.
     
  0.900
pheA
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: mgm:Mmc1_1881 prephenate dehydratase.
 
  
 0.783
Tter_0433
PFAM: aminoglycoside phosphotransferase; KEGG: bcb:BCB4264_A2807 hypothetical protein.
  
    0.710
Tter_0432
PFAM: Amylo-alpha-16-glucosidase; KEGG: aba:Acid345_3259 amylo-alpha-1,6-glucosidase.
       0.660
Tter_2813
PFAM: biotin/lipoyl attachment domain-containing protein; transferase hexapeptide repeat containing protein; KEGG: gur:Gura_1700 serine acetyltransferase-like protein.
  
 
 0.565
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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