Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tter_0752PFAM: domain of unknown function DUF1730; PBS lyase HEAT domain protein repeat-containing protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; HEAT domain containing protein; SMART: PBS lyase HEAT domain protein repeat- containing protein; KEGG: sus:Acid_3576 hypothetical protein. (383 aa)    
Predicted Functional Partners:
Tter_0753
Hypothetical protein.
       0.741
Tter_0751
TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: afw:Anae109_3844 major facilitator transporter.
       0.678
Tter_0876
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: mxa:MXAN_2697 HAD-superfamily hydrolase, subfamily IA, variant 3.
      0.622
queA
S-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
 
   
 0.575
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
     
 0.560
prfB
Bacterial peptide chain release factor 2 (bRF- 2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
       0.508
Tter_0750
PFAM: histone deacetylase superfamily; KEGG: bcb:BCB4264_A4778 acetoin utilization protein AcuC.
       0.503
Tter_0749
Hypothetical protein.
       0.465
Tter_0747
Dithiol-disulfide isomerase involved in polyketide biosynthesis-like protein; KEGG: mxa:MXAN_0351 thioredoxin domain protein.
       0.421
Tter_0334
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: glo:Glov_1076 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
     
 0.415
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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