Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tter_0785KEGG: sfu:Sfum_2104 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; succinate dehydrogenase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase. (576 aa)    
Predicted Functional Partners:
Tter_0784
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: sfu:Sfum_2103 succinate dehydrogenase and fumarate reductase iron-sulfur protein.
 0.999
Tter_0786
KEGG: wbm:Wbm0485 succinate dehydrogenase subunit D SdhD, hydrophobic membrane anchor protein.
 
 0.999
Tter_0787
TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: succinate dehydrogenase, cytochrome b subunit; K00241 succinate dehydrogenase cytochrome b-556 subunit.
 
 0.999
fumC
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
 
 0.994
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.980
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.977
Tter_1549
KEGG: glo:Glov_1316 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family.
    
 0.902
Tter_1539
PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: sat:SYN_00152 NADH:ubiquinone oxidoreductase, NADH-binding subunit.
  
 
 0.861
Tter_2537
PFAM: Rieske [2Fe-2S] domain protein; KEGG: sus:Acid_2926 Rieske (2Fe-2S) domain- containing protein.
  
 
 0.857
Tter_0256
PFAM: aminotransferase class I and II; KEGG: mgm:Mmc1_0698 L-aspartate aminotransferase.
     
 0.806
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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