Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tter_0790Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; response regulator receiver; ATPase associated with various cellular activities AAA_5; SMART: response regulator receiver; AAA ATPase; KEGG: cko:CKO_00549 acetoacetate metabolism regulatory protein AtoC. (466 aa)    
Predicted Functional Partners:
Tter_0789
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: pin:Ping_0978 response regulator receiver modulated diguanylate cyclase.
 
 
0.841
Tter_0291
TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; KEGG: pau:PA14_57940 RNA polymerase factor sigma-54.
 
   
 0.805
Tter_2224
KEGG: mms:mma_0739 sulfonate ABC transporter, periplasmic sulfonate-binding protein SsuA; TIGRFAM: aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SMART: extracellular solute-binding protein family 3.
    
 0.771
Tter_2371
Multi-sensor signal transduction histidine kinase; KEGG: mex:Mext_1455 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
 
 0.621
Tter_2194
KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
  
 
 0.614
Tter_0301
KEGG: bxe:Bxe_A3924 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; ATP-binding region ATPase domain protein; SMART: GAF domain protein; PAC repeat-containing protein; ATP-binding region ATPase domain protein; PAS domain containing protein.
   
 
 0.595
Tter_0442
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); KEGG: tcx:Tcr_1150 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
  
 
 0.591
Tter_0788
PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: mca:MCA3071 isocitrate dehydrogenase, NAD- dependent, putative.
       0.545
Tter_0791
PFAM: protein of unknown function DUF6 transmembrane; KEGG: sfu:Sfum_3638 protein of unknown function DUF6, transmembrane.
       0.535
Tter_2374
Multi-sensor signal transduction histidine kinase; KEGG: mxa:MXAN_7398 sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
 
 
 0.533
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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