STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tter_1075PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; DNA polymerase X; Helix-hairpin-helix DNA-binding class 1; KEGG: sat:SYN_00286 DNA polymerase IV. (584 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.967
lig
DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
  
 0.964
Tter_0145
TIGRFAM: D,D-heptose 1,7-bisphosphate phosphatase; histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: Polynucleotide kinase 3 phosphatase central region; Haloacid dehalogenase domain protein hydrolase; KEGG: D,D-heptose 1,7-bisphosphate phosphatase; K03273 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase.
    
 0.934
Tter_0993
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 0.693
mutS2
MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
  
  
 0.648
Tter_1076
PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: bha:BH0604 methanol dehydrogenase regulatory protein.
       0.543
Tter_0762
PFAM: HhH-GPD family protein; helix-hairpin-helix motif; SMART: HhH-GPD family protein; KEGG: mrd:Mrad2831_5333 helix-hairpin-helix DNA- binding motif-containing protein.
     
 0.520
Tter_1077
PFAM: protein of unknown function DUF58; KEGG: gur:Gura_0188 hypothetical protein.
       0.508
Tter_1078
PFAM: transglutaminase domain protein; SMART: transglutaminase domain protein; KEGG: aba:Acid345_2146 transglutaminase-like.
       0.508
Tter_2641
PFAM: protein of unknown function DUF72; KEGG: protein of unknown function DUF72.
 
     0.493
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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