STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tter_1236PFAM: protein of unknown function DUF1037; KEGG: lch:Lcho_3205 hypothetical protein. (239 aa)    
Predicted Functional Partners:
Tter_1572
PFAM: oxidoreductase domain protein; homoserine dehydrogenase NAD-binding; KEGG: bha:BH0708 hypothetical protein.
 
    0.746
Tter_1938
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: aba:Acid345_1695 sugar phosphate isomerases/epimerases.
 
     0.698
Tter_2606
PFAM: oxidoreductase domain protein; homoserine dehydrogenase NAD-binding; Oxidoreductase domain; KEGG: mlo:mll1511 hypothetical protein.
 
    0.648
Tter_1474
PFAM: oxidoreductase domain protein; aldo/keto reductase; Semialdehyde dehydrogenase NAD - binding; homoserine dehydrogenase NAD-binding; Oxidoreductase domain; KEGG: mlo:mlr6441 oxidoreductase.
 
    0.587
Tter_2265
PFAM: oxidoreductase domain protein; homoserine dehydrogenase NAD-binding; KEGG: rec:RHECIAT_CH0002098 putative dehydrogenase protein.
 
    0.538
Tter_1235
PFAM: protein of unknown function UPF0118; KEGG: bha:BH2921 hypothetical protein.
       0.524
Tter_1237
PFAM: PEGA domain protein; KEGG: bsu:BSU06570 hypothetical protein.
       0.458
menH
Alpha/beta hydrolase fold protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
       0.420
menD
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylic acid synthase/2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
       0.420
Tter_1234
TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: pfl:PFL_3488 salicylate biosynthesis isochorismate synthase.
       0.420
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.