Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tter_1259KEGG: swi:Swit_4521 membrane-like protein. (649 aa)    
Predicted Functional Partners:
Tter_1258
Hypothetical protein; KEGG: mno:Mnod_2311 flagellar hook-associated protein FlgK.
       0.689
Tter_1257
Phage shock protein A, PspA; PFAM: PspA/IM30 family protein; KEGG: hypothetical protein; K03969 phage shock protein A.
       0.616
Tter_1256
Hypothetical protein.
       0.537
Tter_0990
Hypothetical protein.
 
    0.524
Tter_2870
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
   
    0.496
Tter_0918
KEGG: sus:Acid_0799 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; Belongs to the peptidase S26 family.
   
    0.438
Tter_2030
TIGRFAM: peptidase S26B, signal peptidase; PFAM: peptidase S24 and S26 domain protein; KEGG: signal peptidase; K03100 signal peptidase I.
  
    0.438
Tter_1260
KEGG: hypothetical protein.
       0.430
Tter_0291
TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; KEGG: pau:PA14_57940 RNA polymerase factor sigma-54.
   
    0.429
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
    0.416
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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