STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepALeucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (492 aa)    
Predicted Functional Partners:
Tter_0464
KEGG: sse:Ssed_0948 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase.
  
  
 0.927
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.837
Tter_0256
PFAM: aminotransferase class I and II; KEGG: mgm:Mmc1_0698 L-aspartate aminotransferase.
   
  0.820
Tter_1365
PFAM: Polyprenyl synthetase; KEGG: nmn:NMCC_1817 octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
     
 0.709
Tter_1363
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.549
Tter_2605
PFAM: glycoside hydrolase family 3 domain protein; KEGG: hypothetical protein; K01207 beta-N- acetylhexosaminidase.
    
 0.493
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
  
  0.465
Tter_1187
PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: scl:sce8634 bifunctional homocysteine S- methyltransferase/5,10-methylenetetrahydrofolate reductase protein.
     
 0.444
Tter_1362
PFAM: protein of unknown function YGGT; KEGG: noc:Noc_3001 hypothetical protein.
       0.417
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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