STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (281 aa)    
Predicted Functional Partners:
Tter_0599
PFAM: Proline dehydrogenase; KEGG: sus:Acid_2007 L-proline dehydrogenase.
   
 0.937
Tter_0870
PFAM: Aldehyde Dehydrogenase; KEGG: sfu:Sfum_2203 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.910
Tter_2662
KEGG: ret:RHE_PB00090 proline iminopeptidase protein; TIGRFAM: proline-specific peptidase; PFAM: alpha/beta hydrolase fold; Belongs to the peptidase S33 family.
    
  0.902
Tter_0636
PFAM: LOR/SDH bifunctional protein conserved domain protein; KEGG: pca:Pcar_2163 hypothetical protein.
     
  0.900
Tter_0939
Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
 0.884
Tter_1436
KEGG: sfu:Sfum_3649 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein.
     
 0.733
Tter_0474
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: afw:Anae109_0854 glutamate synthase (ferredoxin).
     
 0.559
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.534
Tter_1435
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sfu:Sfum_2007 two component transcriptional regulator, winged helix family.
       0.503
Tter_1362
PFAM: protein of unknown function YGGT; KEGG: noc:Noc_3001 hypothetical protein.
 
    0.486
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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