Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
Tter_1451TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: rms:RMA_0786 dihydrolipoamide dehydrogenase. (466 aa)    
Predicted Functional Partners:
Tter_0092
Dihydrolipoyllysine-residue succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: mxa:MXAN_2668 pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase.
 0.993
Tter_0095
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: bha:BH2761 branched-chain alpha-keto acid dehydrogenase subunit E2.
 0.990
Tter_0332
2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.990
Tter_0094
PFAM: Transketolase central region; Transketolase domain protein; KEGG: bha:BH2762 branched-chain alpha-keto acid dehydrogenase E1.
 0.978
Tter_0333
2-oxoglutarate dehydrogenase, E1 subunit; KEGG: bha:BH2206 alpha-ketoglutarate decarboxylase; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component.
  
 0.978
Tter_0091
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.974
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.969
pdhA
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 
 0.959
Tter_0093
3-methyl-2-oxobutanoate dehydrogenase (2- methylpropanoyl-transferring); PFAM: dehydrogenase E1 component; KEGG: bce:BC4159 2-oxoisovalerate dehydrogenase alpha subunit.
 
 
 0.956
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
 
 0.953
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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