STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tter_1569PFAM: heat shock protein Hsp20; KEGG: Os01g0136100; hypothetical protein; Belongs to the small heat shock protein (HSP20) family. (140 aa)    
Predicted Functional Partners:
Tter_0537
PFAM: heat shock protein Hsp20; KEGG: sal:Sala_0391 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.
  
     0.572
Tter_0372
PFAM: heat shock protein Hsp20; KEGG: afw:Anae109_3080 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.
  
     0.549
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.532
Tter_1349
PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Torsin; UvrB/UvrC protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family.
  
 
 0.532
Tter_1399
PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Torsin; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; KEGG: acp:A2cp1_0414 ATP-dependent chaperone ClpB; Belongs to the ClpA/ClpB family.
  
 
 0.532
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.503
Tter_1570
PFAM: NAD-dependent epimerase/dehydratase; KEGG: sus:Acid_7076 NAD-dependent epimerase/dehydratase.
  
    0.476
hslV
20S proteasome A and B subunits; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
   
  
 0.424
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 
 0.413
Tter_1571
PFAM: oxidoreductase domain protein; homoserine dehydrogenase NAD-binding; KEGG: atc:AGR_L_2949 hypothetical protein.
       0.401
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.