STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (786 aa)    
Predicted Functional Partners:
trmH
tRNA guanosine-2'-O-methyltransferase; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
 
  
 0.864
Tter_1652
PFAM: Dak phosphatase; KEGG: bha:BH2498 hypothetical protein.
  
    0.848
Tter_1649
TIGRFAM: methyltransferase; PFAM: Protein of unknown function methylase putative; methyltransferase small; KEGG: gbm:Gbem_1892 methyltransferase.
       0.802
Tter_1651
TIGRFAM: degV family protein; PFAM: DegV family protein; KEGG: bsu:BSU35480 hypothetical protein.
       0.802
Tter_1760
PFAM: zinc finger CHC2-family protein; SMART: zinc finger CHC2-family protein; KEGG: xfa:XF2122 hypothetical protein.
   
  
 0.633
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
   
 0.599
rpmB
PFAM: ribosomal protein L28; KEGG: ribosomal protein L28; K02902 large subunit ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
     
 0.587
Tter_0993
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
  
 0.578
Tter_1648
Hypothetical protein; KEGG: PLEC1; plectin 1, intermediate filament binding protein 500kDa; K10388 plectin.
       0.562
Tter_1920
KEGG: nmu:Nmul_A2304 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: helicase domain protein; DEAD-like helicase.
   
  
 0.557
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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