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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nfoApurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (296 aa)    
Predicted Functional Partners:
Tter_1686
Hypothetical protein; KEGG: pnu:Pnuc_0979 putative ribonuclease BN.
       0.773
Tter_0762
PFAM: HhH-GPD family protein; helix-hairpin-helix motif; SMART: HhH-GPD family protein; KEGG: mrd:Mrad2831_5333 helix-hairpin-helix DNA- binding motif-containing protein.
  
 
 0.745
Tter_0241
PFAM: periplasmic binding protein; KEGG: pzu:PHZ_c1916 probable periplasmic substrate- binding protein.
      0.692
Tter_1687
KEGG: scl:sce5102 hypothetical protein.
       0.655
Tter_2035
PFAM: glycoside hydrolase 15-related; KEGG: noc:Noc_1617 glycoside hydrolase.
 
      0.616
Tter_1684
PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; protein of unknown function RIO1; Fibronectin type III domain protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; Fibronectin type III domain protein; KEGG: bha:BH2504 serine/threonine protein kinase.
     
 0.579
dinG
DNA polymerase III, epsilon subunit; 3'-5' exonuclease.
  
  
 0.559
Tter_0340
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.481
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.465
Tter_2648
PFAM: helicase domain protein; type III restriction protein res subunit; SMART: helicase domain protein; DEAD-like helicase; KEGG: mgm:Mmc1_2016 helicase domain protein.
  
 
 0.431
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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