| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Tter_0693 | Tter_1476 | Tter_0693 | Tter_1476 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: esa:ESA_03378 nucleotidase. | 0.904 |
| Tter_0693 | pyrF | Tter_0693 | Tter_1293 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: rpi:Rpic_3018 orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.900 |
| Tter_0693 | pyrH | Tter_0693 | Tter_1518 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.900 |
| Tter_0693 | pyrR | Tter_0693 | Tter_1375 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.904 |
| Tter_0693 | upp | Tter_0693 | Tter_1755 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.900 |
| Tter_1374 | guaA | Tter_1374 | Tter_0959 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: atc:AGR_L_3468 putative purine permease YcdG. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.541 |
| Tter_1374 | pyrB | Tter_1374 | Tter_1373 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: atc:AGR_L_3468 putative purine permease YcdG. | KEGG: mpo:Mpop_3512 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.977 |
| Tter_1374 | pyrF | Tter_1374 | Tter_1293 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: atc:AGR_L_3468 putative purine permease YcdG. | TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: rpi:Rpic_3018 orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.847 |
| Tter_1374 | pyrR | Tter_1374 | Tter_1375 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: atc:AGR_L_3468 putative purine permease YcdG. | Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.968 |
| Tter_1374 | upp | Tter_1374 | Tter_1755 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: atc:AGR_L_3468 putative purine permease YcdG. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.701 |
| Tter_1476 | Tter_0693 | Tter_1476 | Tter_0693 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: esa:ESA_03378 nucleotidase. | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.904 |
| Tter_1476 | pyrF | Tter_1476 | Tter_1293 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: esa:ESA_03378 nucleotidase. | TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: rpi:Rpic_3018 orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.902 |
| Tter_1476 | pyrH | Tter_1476 | Tter_1518 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: esa:ESA_03378 nucleotidase. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.901 |
| Tter_1476 | pyrR | Tter_1476 | Tter_1375 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: esa:ESA_03378 nucleotidase. | Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.900 |
| Tter_1476 | upp | Tter_1476 | Tter_1755 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: esa:ESA_03378 nucleotidase. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.906 |
| Tter_2482 | glyA | Tter_2482 | Tter_0031 | TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase; KEGG: YALI0F01628p; K01808 ribose 5-phosphate isomerase B. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.505 |
| Tter_2482 | guaA | Tter_2482 | Tter_0959 | TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase; KEGG: YALI0F01628p; K01808 ribose 5-phosphate isomerase B. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.502 |
| Tter_2482 | upp | Tter_2482 | Tter_1755 | TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase; KEGG: YALI0F01628p; K01808 ribose 5-phosphate isomerase B. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.912 |
| glyA | Tter_2482 | Tter_0031 | Tter_2482 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase; KEGG: YALI0F01628p; K01808 ribose 5-phosphate isomerase B. | 0.505 |
| glyA | guaA | Tter_0031 | Tter_0959 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.636 |