STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfp-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (342 aa)    
Predicted Functional Partners:
Tter_0138
1-phosphofructokinase; KEGG: bcz:BCZK1642 tagatose-6-phosphate kinase, phosphofructokinase I; TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; Belongs to the carbohydrate kinase PfkB family.
  
  
 0.920
Tter_0415
PFAM: Transketolase central region; Transketolase domain protein; KEGG: scl:sce8467 transketolase.
  
 
 0.920
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
  
 
0.920
Tter_0465
PFAM: mannose-6-phosphate isomerase type I; KEGG: aba:Acid345_0569 mannose-6-phosphate isomerase.
    
 0.912
Tter_2456
PFAM: deoxyribose-phosphate aldolase/phospho-2- dehydro-3-deoxyheptonate aldolase; KEGG: rru:Rru_A1345 fructose-bisphosphate aldolase.
    
 0.912
Tter_0164
PFAM: ROK family protein; KEGG: sde:Sde_2639 fructokinase.
    
 0.907
Tter_1238
PFAM: deoxyribose-phosphate aldolase/phospho-2- dehydro-3-deoxyheptonate aldolase; KEGG: sus:Acid_1436 tagatose-bisphosphate aldolase.
    
 0.906
Tter_1528
PFAM: Transketolase domain protein; KEGG: rpc:RPC_3879 transketolase-like.
    
 0.904
Tter_1527
PFAM: Transketolase central region; Transketolase domain protein; KEGG: gur:Gura_0492 transketolase, central region.
    
  0.903
Tter_2457
PFAM: glucose-6-phosphate isomerase; KEGG: aba:Acid345_0653 glucose-6-phosphate isomerase.
     
  0.900
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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