Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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[Homology]
Score
Tter_1923TIGRFAM: 2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; NADP oxidoreductase coenzyme F420-dependent; KEGG: cti:RALTA_B0765 2-hydroxy-3-oxopropionate reductase (tartronate semialdehyde reductase) (TSAR). (296 aa)    
Predicted Functional Partners:
Tter_1924
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: mno:Mnod_3088 hydroxypyruvate isomerase; Belongs to the hyi family.
 
 0.991
Tter_0350
Glyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: dal:Dalk_2294 glyoxylate reductase.
    
 0.915
Tter_0099
Hydroxypyruvate reductase; PFAM: MOFRL domain protein; KEGG: dal:Dalk_0946 hydroxypyruvate reductase.
    
 0.910
Tter_2181
PFAM: HpcH/HpaI aldolase; KEGG: bra:BRADO2598 putative aldolase; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.618
Tter_1922
Hypothetical protein.
       0.538
Tter_1925
PFAM: oxidoreductase domain protein; homoserine dehydrogenase NAD-binding; Oxidoreductase domain; KEGG: mes:Meso_4484 oxidoreductase-like.
       0.532
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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