Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tter_1979PFAM: 6-phosphogluconate dehydrogenase NAD-binding; NADP oxidoreductase coenzyme F420-dependent; KEGG: dvm:DvMF_2320 6-phosphogluconate dehydrogenase NAD-binding. (288 aa)    
Predicted Functional Partners:
Tter_1619
PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: rec:RHECIAT_CH0003763 probable biotin carboxylase protein.
  
 
 0.832
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.825
Tter_0095
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: bha:BH2761 branched-chain alpha-keto acid dehydrogenase subunit E2.
     
 0.807
Tter_1980
PFAM: Cupin 2 conserved barrel domain protein; KEGG: bra:BRADO3800 hypothetical protein.
       0.665
Tter_1978
PFAM: Creatininase; KEGG: aba:Acid345_1632 creatininase.
       0.545
Tter_1977
PFAM: Luciferase-like monooxygenase; KEGG: swi:Swit_0704 luciferase family protein.
       0.447
Tter_1924
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: mno:Mnod_3088 hydroxypyruvate isomerase; Belongs to the hyi family.
  
 0.436
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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