STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
fniIsopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (349 aa)    
Predicted Functional Partners:
Tter_1465
PFAM: Polyprenyl synthetase; KEGG: GGPS; geranylgeranyl diphosphate synthase; K00795 geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
 
 
 0.934
ispH
Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
    
 0.927
Tter_2047
PFAM: UbiA prenyltransferase; KEGG: afr:AFE_0592 4-hydroxybenzoate polyprenyl transferase.
    
 0.879
Tter_2046
PFAM: Squalene/phytoene synthase; KEGG: bav:BAV2418 phytoene synthase.
  
  
 0.827
Tter_2045
TIGRFAM: phytoene desaturase; PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: mxa:MXAN_0895 phytoene desaturase.
  
  
 0.791
Tter_2002
TIGRFAM: mevalonate kinase; PFAM: GHMP kinase domain protein; GHMP kinase; KEGG: scl:sce4205 hypothetical protein.
 
  
 0.727
Tter_2125
PFAM: FAD linked oxidase domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: noc:Noc_0464 hypothetical protein.
  
 0.620
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.557
Tter_0163
Alanine--glyoxylate transaminase; PFAM: aminotransferase class V; KEGG: ade:Adeh_2994 alanine-glyoxylate aminotransferase.
  
 0.523
Tter_1351
PFAM: aminotransferase class V; KEGG: nwi:Nwi_2413 aminotransferase, class V.
  
 0.523
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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