Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tter_2112Signal transduction histidine kinase, LytS; KEGG: ecw:EcE24377A_3259 hypothetical protein. (208 aa)    
Predicted Functional Partners:
Tter_2111
PFAM: cobalt transport protein; KEGG: vfm:VFMJ11_1660 ABC-type cobalt transport system, permease component.
   
 0.980
Tter_2110
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: vha:VIBHAR_05108 ATP-binding ABC transporter.
 
     0.895
Tter_0395
SMART: Ankyrin; KEGG: bcz:pE33L466_0197 ankyrin repeat-containing protein.
  
 0.594
Tter_0547
PFAM: WD-40 repeat protein; SMART: WD-40 repeat protein; KEGG: hypothetical protein.
    
 0.594
Tter_2648
PFAM: helicase domain protein; type III restriction protein res subunit; SMART: helicase domain protein; DEAD-like helicase; KEGG: mgm:Mmc1_2016 helicase domain protein.
   
 0.584
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.578
Tter_0750
PFAM: histone deacetylase superfamily; KEGG: bcb:BCB4264_A4778 acetoin utilization protein AcuC.
    
 0.550
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.538
Tter_0370
PFAM: cobalt transport protein; KEGG: bha:BH0166 hypothetical protein.
 
   
 0.524
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.516
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
Server load: low (16%) [HD]