STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tter_2174PFAM: protein of unknown function DUF214; KEGG: bsu:BSU34690 hypothetical protein. (635 aa)    
Predicted Functional Partners:
Tter_2175
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bsu:BSU34700 hypothetical protein.
 
 0.984
Tter_2176
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: bsu:BSU34710 hypothetical protein.
 
 
 
 0.898
Tter_2177
Two component transcriptional regulator, winged helix family; PFAM: transcriptional regulator domain protein; response regulator receiver; SMART: response regulator receiver; KEGG: bcb:BCB4264_A4557 DNA-binding response regulator.
 
     0.875
Tter_0275
TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: aba:Acid345_3531 secretion protein HlyD.
  
 
 0.799
Tter_0277
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ccs:CCNA_02006 lipoprotein releasing system ATP-binding protein LolD.
 
 
 0.737
Tter_0278
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: azo:azo3286 ABC transporter ATP-binding protein.
 
 
 0.737
Tter_2173
PFAM: Methyltransferase type 11; methyltransferase small; Methionine biosynthesis MetW protein; Cyclopropane- fatty-acyl-phospholipid synthase; UbiE/COQ5 methyltransferase; thiopurine S-methyltransferase; Methyltransferase type 12; KEGG: bha:BH2887 hypothetical protein.
 
    0.657
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.478
Tter_1742
Hypothetical protein.
 
  
 0.443
Tter_2194
KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
   
 
 0.435
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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