Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Tter_2177Two component transcriptional regulator, winged helix family; PFAM: transcriptional regulator domain protein; response regulator receiver; SMART: response regulator receiver; KEGG: bcb:BCB4264_A4557 DNA-binding response regulator. (235 aa)    
Predicted Functional Partners:
Tter_2176
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: bsu:BSU34710 hypothetical protein.
 
 0.969
Tter_2194
KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
 0.897
Tter_2174
PFAM: protein of unknown function DUF214; KEGG: bsu:BSU34690 hypothetical protein.
 
   
 0.877
Tter_2175
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bsu:BSU34700 hypothetical protein.
 
   
 0.793
Tter_2371
Multi-sensor signal transduction histidine kinase; KEGG: mex:Mext_1455 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
 0.770
Tter_1097
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: sus:Acid_6896 heavy metal sensor signal transduction histidine kinase.
 
 
 0.720
Tter_0290
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mxa:MXAN_0643 sensory box histidine kinase.
 
 0.718
Tter_1446
Histidine kinase; KEGG: pca:Pcar_3082 two component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.
 
 0.689
Tter_1131
KEGG: mxa:MXAN_0347 sensory box histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein.
 
 
 0.688
Tter_1029
KEGG: rpi:Rpic_4983 integral membrane sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein.
 
 
 0.680
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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