Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tter_2457PFAM: glucose-6-phosphate isomerase; KEGG: aba:Acid345_0653 glucose-6-phosphate isomerase. (263 aa)    
Predicted Functional Partners:
Tter_2459
PFAM: ROK family protein; KEGG: aba:Acid345_0651 sugar kinase.
    
 0.977
Tter_2456
PFAM: deoxyribose-phosphate aldolase/phospho-2- dehydro-3-deoxyheptonate aldolase; KEGG: rru:Rru_A1345 fructose-bisphosphate aldolase.
    
 0.951
Tter_0465
PFAM: mannose-6-phosphate isomerase type I; KEGG: aba:Acid345_0569 mannose-6-phosphate isomerase.
    
  0.912
Tter_0415
PFAM: Transketolase central region; Transketolase domain protein; KEGG: scl:sce8467 transketolase.
    
  0.909
Tter_0018
PFAM: ROK family protein; KEGG: mlo:mlr7234 glucose kinase.
    
 0.904
Tter_0164
PFAM: ROK family protein; KEGG: sde:Sde_2639 fructokinase.
    
 0.904
Tter_1197
PFAM: ROK family protein; KEGG: aba:Acid345_3865 glucokinase.
    
 0.904
Tter_2139
PFAM: ROK family protein; KEGG: gox:GOX1182 putative glucokinase.
    
 0.904
Tter_0139
Glutamine--fructose-6-phosphate transaminase (isomerizing); PFAM: sugar isomerase (SIS); KEGG: rlt:Rleg2_4761 sugar isomerase (SIS).
   
 
  0.902
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
     
 0.901
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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