STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tter_2737Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: eba:ebA4598 cystathionine beta-lyase, putative, gene: MetC. (391 aa)    
Predicted Functional Partners:
Tter_1187
PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: scl:sce8634 bifunctional homocysteine S- methyltransferase/5,10-methylenetetrahydrofolate reductase protein.
 
 0.999
metE
5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.956
Tter_2133
PFAM: homocysteine S-methyltransferase; KEGG: hypothetical protein.
 
 
 0.947
Tter_0434
PFAM: aminotransferase class I and II; KEGG: sus:Acid_3616 aminotransferase.
 
 
 0.930
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
 0.926
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
 
 0.913
Tter_1226
TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: acp:A2cp1_4094 thioredoxin reductase.
   
 
 0.913
Tter_2363
PFAM: GAF domain protein; SMART: GAF domain protein; KEGG: aba:Acid345_2653 putative GAF sensor protein.
     
 0.902
Tter_0985
PFAM: CoA-binding domain protein; KEGG: sus:Acid_6492 CoA-binding domain-containing protein.
 
      0.899
Tter_1314
TIGRFAM: cysteine synthase; cysteine synthase B; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sus:Acid_0758 cysteine synthase.
 
 0.835
Your Current Organism:
Thermobaculum terrenum
NCBI taxonomy Id: 525904
Other names: T. terrenum ATCC BAA-798, Thermobaculum terrenum ATCC BAA-798, Thermobaculum terrenum YNP1, Thermobaculum terrenum str. ATCC BAA-798, Thermobaculum terrenum strain ATCC BAA-798
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