STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (458 aa)    
Predicted Functional Partners:
Afer_0002
KEGG: rxy:Rxyl_0002 DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta chain; SMART: DNA polymerase III beta chain.
 
 
 0.994
recF
DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.
  
 0.952
Afer_0041
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
 
 
 
 0.938
Afer_0005
KEGG: ace:Acel_0005 DNA gyrase subunit B; TIGRFAM: DNA gyrase, B subunit; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; ATP-binding region ATPase domain protein; DNA gyrase subunit B domain protein; TOPRIM domain protein; SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein.
 
  
 0.835
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.699
Afer_0006
KEGG: chy:CHY_2704 DNA gyrase, A subunit; TIGRFAM: DNA gyrase, A subunit; PFAM: DNA gyrase/topoisomerase IV subunit A; DNA gyrase repeat beta-propeller; SMART: DNA gyrase/topoisomerase IV subunit A.
     
 0.688
Afer_2030
parB-like partition protein; KEGG: ace:Acel_2154 chromosome segregation DNA- binding protein; TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; Belongs to the ParB family.
 
  
 0.657
Afer_2031
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: cth:Cthe_2377 chromosome segregation ATPase.
 
 
 0.644
rpmH
TIGRFAM: ribosomal protein L34; PFAM: ribosomal protein L34; KEGG: fra:Francci3_4548 50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
  
  
 0.626
Afer_1026
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerization region; Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: cef:CE0339 putative pyridine nucleotide- disulphide oxidoreductase.
  
    0.614
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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