Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Afer_0021KEGG: aau:AAur_3217 hypothetical protein. (573 aa)    
Predicted Functional Partners:
Afer_0022
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: bln:Blon_0041 hypothetical protein.
 
  
 0.977
Afer_0896
PFAM: Tetratricopeptide TPR_2 repeat protein; Tetratricopeptide TPR_4; KEGG: stp:Strop_1906 tetratricopeptide TPR_4.
  
 
 0.779
Afer_0020
Chitinase; KEGG: aau:AAur_3218 putative glycosyl hydrolase family protein; PFAM: Carbohydrate-binding family V/XII; SMART: Carbohydrate-binding family V/XII.
       0.530
Afer_0129
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: afe:Lferr_1378 cobyrinic acid ac-diamide synthase.
  
 
 0.463
Afer_2031
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: cth:Cthe_2377 chromosome segregation ATPase.
  
 
 0.463
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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