Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0027TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; multi antimicrobial extrusion protein MatE; KEGG: fal:FRAAL6865 hypothetical protein. (535 aa)    
Predicted Functional Partners:
Afer_0025
PFAM: GCN5-related N-acetyltransferase; KEGG: cau:Caur_1705 GCN5-related N- acetyltransferase.
 
     0.808
Afer_0026
Hypothetical protein; KEGG: GF17743 gene product from transcript GF17743- RA.
       0.807
Afer_0028
TIGRFAM: degV family protein; PFAM: DegV family protein; KEGG: hau:Haur_0363 DegV family protein.
       0.807
Afer_0023
TIGRFAM: tRNA adenylyltransferase; metal dependent phophohydrolase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; KEGG: sgr:SGR_3683 putative RNA nucleotidyltransferase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
 
     0.678
Afer_0030
KEGG: fra:Francci3_4536 thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase.
     
 0.638
Afer_0029
Hypothetical protein.
       0.601
Afer_0032
PFAM: Peptidoglycan-binding domain 1 protein; KEGG: ace:Acel_2150 cell wall hydrolase/autolysin.
 
   
 0.555
Afer_1003
PFAM: cell cycle protein; KEGG: fal:FRAAL6752 putative cell division protein FtsW; Belongs to the SEDS family.
 
   
 0.552
Afer_0024
PFAM: histone deacetylase superfamily; KEGG: sul:SYO3AOP1_1212 histone deacetylase superfamily.
       0.549
murA
UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
 
   
 0.537
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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