Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Afer_0030KEGG: fra:Francci3_4536 thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase. (320 aa)    
Predicted Functional Partners:
Afer_0031
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: mmi:MMAR_5478 thioredoxin TrxC; Belongs to the thioredoxin family.
 
 
 0.994
Afer_0567
Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
 
 
  0.917
Afer_0859
Peroxidase; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: xau:Xaut_2363 peroxidase.
  
 
 0.912
Afer_1377
PFAM: ferredoxin; Oxidoreductase FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: dar:Daro_0368 ferredoxin:oxidoreductase FAD/NAD(P)-binding:oxidoreductase FAD-binding region.
   
 
 0.878
Afer_1561
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: tfu:Tfu_0172 thioredoxin; Belongs to the thioredoxin family.
  
 
 0.861
Afer_1305
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: cau:Caur_0205 thioredoxin domain-containing protein.
  
 
 0.858
Afer_0338
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: mgm:Mmc1_3503 periplasmic protein thiol-- disulphide oxidoreductase DsbE.
  
 
 0.776
Afer_1710
PFAM: Redoxin domain protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Thioredoxin domain; KEGG: ttj:TTHA1728 hypothetical protein.
  
 
 0.776
Afer_0029
Hypothetical protein.
       0.748
Afer_0728
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: mxa:MXAN_2588 molybdopterin biosynthesis protein MoeB.
  
  
 0.693
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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