STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0033Transcriptional regulator, XRE family; PFAM: DNA polymerase beta domain protein region; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: cmi:CMM_2452 Cro/CI family transcriptional regulator/nucleotidyltransferase. (169 aa)    
Predicted Functional Partners:
Afer_0034
PFAM: protein of unknown function DUF86; KEGG: tel:tll2231 hypothetical protein.
 
  
 0.965
Afer_1341
PFAM: protein of unknown function DUF86; KEGG: mla:Mlab_0885 hypothetical protein.
 
  
 0.855
Afer_1342
PFAM: DNA polymerase beta domain protein region; KEGG: rca:Rcas_2416 DNA polymerase beta subunit.
  
     0.773
Afer_1495
PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: kra:Krad_1362 Cys/Met metabolism pyridoxal- phosphate-dependent protein.
  
  
 0.641
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.553
Afer_0459
TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase; KEGG: rxy:Rxyl_0815 inositol-5-monophosphate dehydrogenase.
     
 0.552
Afer_1167
PFAM: plasmid stabilization system; KEGG: neu:NE0476 hypothetical protein.
     
 0.547
Afer_1648
TIGRFAM: death-on-curing family protein; PFAM: filamentation induced by cAMP protein Fic; KEGG: rca:Rcas_2210 death-on-curing family protein.
 
     0.459
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.