Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Afer_0038PFAM: transcriptional regulator PadR family protein; KEGG: fra:Francci3_4528 PadR family transcriptional regulator. (197 aa)    
Predicted Functional Partners:
Afer_0037
PFAM: Myo-inositol-1-phosphate synthase; Myo- inositol-1-phosphate synthase GAPDH domain protein; KEGG: saq:Sare_5081 myo-inositol-1-phosphate synthase.
 
   
 0.800
Afer_1448
KEGG: fre:Franean1_0153 major facilitator transporter.
  
     0.731
Afer_0039
KEGG: ace:Acel_2136 hypothetical protein.
 
     0.685
Afer_0757
KEGG: sgr:SGR_5851 hypothetical protein.
  
     0.681
Afer_1197
KEGG: msm:MSMEG_6365 hypothetical protein.
  
     0.653
Afer_1224
PFAM: lipid A biosynthesis acyltransferase; KEGG: tfu:Tfu_2102 lipid A biosynthesis lauroyl acyltransferase.
  
     0.454
Afer_1917
TIGRFAM: anti-sigma factor; KEGG: saq:Sare_4094 anti-sigma factor RshA.
  
     0.454
Afer_0274
Transcriptional regulator, XRE family; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: art:Arth_0847 transcriptional regulator, XRE family with cupin sensor.
  
  
 0.433
panB
3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
       0.405
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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