STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0050PFAM: Secreted repeat of unknown function; KEGG: ace:Acel_0027 hypothetical protein. (221 aa)    
Predicted Functional Partners:
Afer_0049
PFAM: sodium/hydrogen exchanger; KEGG: ank:AnaeK_3726 sodium/hydrogen exchanger.
       0.546
Afer_1384
PFAM: metallophosphoesterase; KEGG: nca:Noca_3235 metallophosphoesterase.
  
     0.536
Afer_1300
PFAM: FMN-binding domain protein; KEGG: ace:Acel_0050 FMN-binding domain-containing protein.
  
     0.493
Afer_1432
TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; PFAM: Male sterility domain; Haloacid dehalogenase domain protein hydrolase; NAD-dependent epimerase/dehydratase; KEGG: fal:FRAAL3759 putative fatty acyl CoA reductase.
  
     0.454
Afer_1205
KEGG: sco:SCO4586 ABC transporter integral membrane protein.
  
     0.442
Afer_0665
PFAM: NMT1/THI5 like domain protein; KEGG: rpc:RPC_0844 ABC transporter substrate- binding protein.
  
     0.427
Afer_1600
Hypothetical protein; KEGG: glycoside hydrolase family 5 protein.
  
     0.418
Afer_0445
PFAM: membrane protein of uknown function UCP014873; KEGG: bcs:BCAN_B0338 hypothetical protein.
  
     0.412
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.