Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0076PFAM: Pyridoxal-dependent decarboxylase; KEGG: fra:Francci3_0279 pyridoxal-dependent decarboxylase. (458 aa)    
Predicted Functional Partners:
Afer_0700
PFAM: aminotransferase class-III; KEGG: rca:Rcas_3219 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.924
Afer_0941
PFAM: aminotransferase class-III; KEGG: sen:SACE_3418 aminotransferase class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.922
Afer_1662
PFAM: aminotransferase class-III; KEGG: art:Arth_1499 acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
  
 0.899
Afer_0077
PFAM: histidine triad (HIT) protein; KEGG: pna:Pnap_4872 histidine triad (HIT) protein.
       0.775
Afer_0575
PFAM: aminotransferase class-III; KEGG: ace:Acel_1287 hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     0.709
Afer_0074
PFAM: Patatin; KEGG: mmi:MMAR_2150 alpha-beta hydrolase superfamily esterase.
 
     0.608
Afer_0075
Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; regulatory protein Crp; SMART: regulatory protein MarR; KEGG: esi:Exig_2989 MarR family transcriptional regulator.
       0.538
Afer_0574
PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: sgr:SGR_1846 AsnC family transcriptional regulator.
 
     0.445
Afer_1190
PFAM: aminotransferase class-III; KEGG: sen:SACE_3329 adenosylmethionine-8-amino-7- oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
      0.437
Afer_1378
PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; KEGG: ote:Oter_0715 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.434
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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