STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0079PFAM: CoA-binding domain protein; KEGG: spe:Spro_1762 CoA-binding domain-containing protein. (145 aa)    
Predicted Functional Partners:
Afer_1495
PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: kra:Krad_1362 Cys/Met metabolism pyridoxal- phosphate-dependent protein.
 
      0.871
Afer_0080
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: nca:Noca_1946 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
       0.773
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
       0.562
Afer_0078
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: saq:Sare_2891 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
       0.531
Afer_0199
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: fra:Francci3_2661 ferric uptake regulator family protein; Belongs to the Fur family.
  
    0.513
Afer_0294
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: nfa:nfa3250 putative ferric uptake regulator; Belongs to the Fur family.
  
    0.513
Afer_1453
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: cts:Ctha_1302 ferric uptake regulator, Fur family; Belongs to the Fur family.
  
    0.513
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.