STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pheAPFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: ade:Adeh_1779 prephenate dehydratase. (306 aa)    
Predicted Functional Partners:
Afer_1531
PFAM: aminotransferase class I and II; KEGG: rsa:RSal33209_0984 aspartate aminotransferase.
 
 
 0.989
Afer_1157
PFAM: Prephenate dehydrogenase; KEGG: krh:KRH_15220 prephenate dehydrogenase.
 
 
 0.969
Afer_1158
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: bvi:Bcep1808_0964 chorismate mutase / prephenate dehydratase.
  
  
 
0.926
hisC
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: fra:Francci3_3026 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.918
Afer_1355
TIGRFAM: chorismate mutase; PFAM: Chorismate mutase of the AroH class; KEGG: nca:Noca_2499 chorismate mutase.
    
 0.911
katG
Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
     
  0.800
Afer_1717
PFAM: 3-dehydroquinate synthase; KEGG: saq:Sare_1253 3-dehydroquinate synthase.
 
  
 0.662
Afer_0098
PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; KEGG: mrd:Mrad2831_1356 putative circadian phase modifier CpmA-like protein.
       0.629
Afer_0099
PFAM: protein of unknown function DUF111; KEGG: mem:Memar_2158 hypothetical protein.
       0.629
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
   
 0.574
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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