Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0099PFAM: protein of unknown function DUF111; KEGG: mem:Memar_2158 hypothetical protein. (386 aa)    
Predicted Functional Partners:
Afer_0098
PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; KEGG: mrd:Mrad2831_1356 putative circadian phase modifier CpmA-like protein.
 
  
 0.984
Afer_1841
KEGG: scl:sce5850 hypothetical protein.
  
 0.964
Afer_0100
PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: acr:Acry_0942 alpha/beta hydrolase domain- containing protein.
       0.712
Afer_1430
KEGG: nca:Noca_2000 hypothetical protein.
 
  
 0.648
pheA
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: ade:Adeh_1779 prephenate dehydratase.
       0.629
Afer_1306
PFAM: aldo/keto reductase; KEGG: nca:Noca_0658 aldo/keto reductase.
 
    0.489
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
 
      0.481
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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