Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Afer_0105TIGRFAM: crotonyl-CoA reductase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: stp:Strop_3612 crotonyl-CoA reductase. (464 aa)    
Predicted Functional Partners:
Afer_0104
TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: pho:PH0272 hypothetical protein.
  
 
 0.843
Afer_0223
KEGG: saq:Sare_4003 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12- binding domain protein.
   
 0.822
Afer_1603
PFAM: MaoC domain protein dehydratase; KEGG: saq:Sare_0676 dehydratase.
 
 
 0.765
Afer_1820
PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: art:Arth_0066 alcohol dehydrogenase GroES domain protein.
  
     0.625
Afer_1779
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sen:SACE_6207 enoyl-CoA hydratase-isomerase; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 
 0.593
Afer_0106
KEGG: fal:FRAAL5910 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.536
Afer_1025
KEGG: ace:Acel_1476 vitamin B12-dependent ribonucleotide reductase; TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; PFAM: Ribonucleotide reductase class II vitamin B12- dependent; ribonucleotide reductase large subunit; SMART: Hedgehog/intein hint domain protein.
  
 
   0.493
Afer_1770
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: lic:LIC13009 acyl-CoA dehydrogenase.
 
 
 0.449
Afer_0107
PFAM: Methyltransferase type 11; glycosyl transferase group 1; Methionine biosynthesis MetW protein; Methyltransferase type 12; KEGG: pcu:pc1183 putative mannosyltransferase.
       0.432
Afer_0094
TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: MaoC domain protein dehydratase; Aldehyde Dehydrogenase; KEGG: nfa:nfa21550 bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase.
  
 
 0.407
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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