node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Afer_0111 | Afer_0723 | Afer_0111 | Afer_0723 | KEGG: kra:Krad_0463 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.802 |
Afer_0111 | Afer_0959 | Afer_0111 | Afer_0959 | KEGG: kra:Krad_0463 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: ret:RHE_PE00440 L-aspartate oxidase. | 0.808 |
Afer_0111 | Afer_1070 | Afer_0111 | Afer_1070 | KEGG: kra:Krad_0463 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | Asparaginase; PFAM: peptidase T2 asparaginase 2; KEGG: rca:Rcas_4430 asparaginase. | 0.802 |
Afer_0111 | Afer_1531 | Afer_0111 | Afer_1531 | KEGG: kra:Krad_0463 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | PFAM: aminotransferase class I and II; KEGG: rsa:RSal33209_0984 aspartate aminotransferase. | 0.843 |
Afer_0111 | Afer_1702 | Afer_0111 | Afer_1702 | KEGG: kra:Krad_0463 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; KEGG: ttj:TTHA0782 aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.804 |
Afer_0111 | Afer_1813 | Afer_0111 | Afer_1813 | KEGG: kra:Krad_0463 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: fal:FRAAL5951 homoserine dehydrogenase. | 0.939 |
Afer_0111 | argG | Afer_0111 | Afer_1659 | KEGG: kra:Krad_0463 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | KEGG: fra:Francci3_3169 argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: argininosuccinate synthase; ExsB family protein; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.857 |
Afer_0111 | asd | Afer_0111 | Afer_0112 | KEGG: kra:Krad_0463 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.998 |
Afer_0111 | lysA | Afer_0111 | Afer_1814 | KEGG: kra:Krad_0463 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.972 |
Afer_0111 | purA | Afer_0111 | Afer_1958 | KEGG: kra:Krad_0463 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.827 |
Afer_0723 | Afer_0111 | Afer_0723 | Afer_0111 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: kra:Krad_0463 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.802 |
Afer_0723 | Afer_1813 | Afer_0723 | Afer_1813 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: fal:FRAAL5951 homoserine dehydrogenase. | 0.969 |
Afer_0723 | asd | Afer_0723 | Afer_0112 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.731 |
Afer_0959 | Afer_0111 | Afer_0959 | Afer_0111 | L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: ret:RHE_PE00440 L-aspartate oxidase. | KEGG: kra:Krad_0463 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.808 |
Afer_0959 | Afer_1070 | Afer_0959 | Afer_1070 | L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: ret:RHE_PE00440 L-aspartate oxidase. | Asparaginase; PFAM: peptidase T2 asparaginase 2; KEGG: rca:Rcas_4430 asparaginase. | 0.900 |
Afer_0959 | Afer_1531 | Afer_0959 | Afer_1531 | L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: ret:RHE_PE00440 L-aspartate oxidase. | PFAM: aminotransferase class I and II; KEGG: rsa:RSal33209_0984 aspartate aminotransferase. | 0.812 |
Afer_0959 | Afer_1702 | Afer_0959 | Afer_1702 | L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: ret:RHE_PE00440 L-aspartate oxidase. | PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; KEGG: ttj:TTHA0782 aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.900 |
Afer_0959 | argG | Afer_0959 | Afer_1659 | L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: ret:RHE_PE00440 L-aspartate oxidase. | KEGG: fra:Francci3_3169 argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: argininosuccinate synthase; ExsB family protein; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.909 |
Afer_0959 | purA | Afer_0959 | Afer_1958 | L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: ret:RHE_PE00440 L-aspartate oxidase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.911 |
Afer_1070 | Afer_0111 | Afer_1070 | Afer_0111 | Asparaginase; PFAM: peptidase T2 asparaginase 2; KEGG: rca:Rcas_4430 asparaginase. | KEGG: kra:Krad_0463 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.802 |